LACTOSE INTOLERANCE AND ITS EFFECT ON PLASMA GLUCOSE LEVELS AND OTHER BIOCHEMICAL PARAMETERS

Aim: To determine the effect of lactose intolerance on serum glucose levels and related biochemical parameters in adult population who refrain from consuming milk products.Material Method: This retrospective, observational study was conducted a tertiary care hospital between January 2021 December with 296 participants. Plasma glucose, calcium, 25-hydroxyvitamin D3, folate, vitamin B12, thyroid- stimulating hormone (TSH), ferritin were controlled. Patients positive test results accepted as group negative control group, data two groups compared.Results: Of total participants 212 (71.7%) found to have 84 (28.3%) be normal. In intolerant blood significantly lower than (5.14±0.53 mmol/L versus 5.47±0.54 mmol/L, p<0.001). 29 (13.7%) patients, 18 (21.4%) patients having type 2 diabetes mellitus. diabetic both fasting (5.68±0.49 6.30±0.59 p<0.001) glycated hemoglobin also (6.78±1.08 7.62±0.96, p<0.001).Conclusions: this study, based upon findings people insufficient consumption, any decrease calcium or D not observed. Lactose may compared lactase persistent people. Larger-scale long-term studies are needed demonstrate that persistence is an independent risk factor for development diabetes.